Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250859 | 0.88 | RIOK2 (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3250544 | 0.85 | MMP2 (0.48) | TLR8TLR7CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3249879 | 0.85 | JAK2 (0.42) | CSF1RHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3252380 | 0.85 | CSF1R (0.43) | CSF1RHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3253850 | 0.84 | SCN9A (0.38) | CSF1RHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3249865 | 0.83 | KDM4E (0.40) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL3254886 | 0.83 | PAK1 (0.42) | CSF1RHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3244562 | 0.82 | CCNC (0.38) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL3252050 | 0.82 | GAA (0.40) | CSF1RHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3250692 | 0.82 | HPGD (0.34) | CSF1RHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |