SCHEMBL3246792

SCHEMBL3246792

Clc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)n1-c1nc(-c2ccccc2)c(-c2ccccc2)n1-c1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
HSD11B1 P28845 2/20 0.40
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CYP2A6 P11509 1/20 0.38
TOP2A P11388 2/20 0.37
LMNA P02545 3/20 0.37
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22507458 0.92 BCHE (0.47) BCHEACHEHSD11B1ESR1ESR2
SCHEMBL10071744 0.86 BCHE (0.54) BCHEACHEHSD11B1ESR1ESR2
SCHEMBL4205066 0.83 HSD11B1 (0.45) BCHEACHEHSD11B1ALDH1A1SMN1; SMN2
SCHEMBL3249022 0.80 PDGFRB (0.47) LMNAALDH1A1SMN1; SMN2POLBKMT2A
SCHEMBL4096729 0.79 GRM1 (0.39) BCHEACHEALDH1A1HPGDPTGS2
SCHEMBL28949210 0.79 POLB (0.47) BCHEACHEALDH1A1POLBKMT2A
SCHEMBL14113001 0.77 HCAR1 (0.45) BCHEACHELMNAALDH1A1SMN1; SMN2
SCHEMBL15753777 0.77 BCHE (0.47) BCHEACHETOP2AMGAMGAA
SCHEMBL29732755 0.77 HSD11B1 (0.49) BCHEACHEHSD11B1CYP2A6LMNA
SCHEMBL63728 0.77 HSD11B1 (0.49) BCHEACHEHSD11B1CYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
EP-1553450-B1 Process for preparing plugged-through-hole printed wiring board and plugged-through-hole printed wiring board SAN EI KAGAKU CO (JP) 2010-05-26 EP disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-1298155-A1 Photo-setting and thermosetting resin composition, process for preparing plugged-through-hole printed wiring board, and plugged-through-hole printed wiring board San-Ei Kagaku Co. Ltd. (JP) 2003-04-02 EP disclosed