SCHEMBL28949210

SCHEMBL28949210

O=C(O)c1ccccc1-n1c(-c2ccccc2Cl)nc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
KMT2A Q03164 1/20 0.44
MYC P01106 3/20 0.43
NR4A1 P22736 1/20 0.43
MDM2 Q00987 2/20 0.42
ALDH1A1 P00352 3/20 0.42
NR4A2 P43354 2/20 0.42
KDM4E B2RXH2 2/20 0.42
RXFP1 Q9HBX9 1/20 0.42
RECQL P46063 1/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
NOTUM Q6P988 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
DHODH Q02127 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30298822 0.89 MDM2 (0.44) POLBMYCNR4A1MDM2KDM4E
SCHEMBL22507458 0.86 BCHE (0.47) POLBKMT2AALDH1A1NR4A2KDM4E
SCHEMBL28949223 0.84 KMT2A (0.40) KMT2AMYCNR4A1MDM2ALDH1A1
SCHEMBL3246792 0.79 BCHE (0.46) POLBKMT2AALDH1A1BCHEACHE
SCHEMBL15753777 0.77 BCHE (0.47) MDM2BCHEACHERXRARXRB
SCHEMBL31351857 0.77 FABP4 (0.45) POLBKMT2AALDH1A1NR4A2KDM4E
SCHEMBL28949240 0.74 LMNA (0.56) KMT2AALDH1A1NR4A2KDM4ERXFP1
SCHEMBL29732755 0.74 HSD11B1 (0.49) ALDH1A1NR4A2KDM4ERXFP1BCHE
SCHEMBL63728 0.74 HSD11B1 (0.49) ALDH1A1NR4A2KDM4ERXFP1BCHE
SCHEMBL28872532 0.74 FABP4 (0.43) POLBKMT2ANR4A1ALDH1A1NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694352-B Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2023-04-07 CN disclosed
CN-115536589-A Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2022-12-30 CN disclosed