SCHEMBL63728

SCHEMBL63728

Clc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)n1-n1c(-c2ccccc2Cl)nc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.49
CYP2A6 P11509 1/20 0.47
LMNA P02545 2/20 0.44
ALDH1A1 P00352 4/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 2/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
MAPK13 O15264 1/20 0.41
RAF1 P04049 1/20 0.41
MAPK12 P53778 1/20 0.41
MAPK11 Q15759 1/20 0.41
MAPK14 Q16539 1/20 0.41
KDM4E B2RXH2 3/20 0.41
PKM P14618 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732755 1.00 HSD11B1 (0.49) HSD11B1CYP2A6LMNAALDH1A1NPC1
SCHEMBL4622519 0.87 HSD11B1 (0.41) HSD11B1CYP2A6LMNAALDH1A1NPC1
SCHEMBL11635736 0.85 HSD11B1 (0.47) HSD11B1CYP2A6LMNAALDH1A1NPC1
SCHEMBL31467384 0.84 HSD11B1 (0.54) HSD11B1LMNAALDH1A1NPC1RAB9A
SCHEMBL2689067 0.84 HSD11B1 (0.54) HSD11B1LMNAALDH1A1NPC1RAB9A
SCHEMBL11640258 0.84 HSD11B1 (0.46) HSD11B1CYP2A6LMNAALDH1A1NPC1
SCHEMBL28949240 0.84 LMNA (0.56) HSD11B1CYP2A6LMNAALDH1A1NPC1
SCHEMBL7897274 0.82 L3MBTL1 (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL62627 0.82 L3MBTL1 (0.50) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL29732925 0.82 L3MBTL1 (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107556183-A The synthetic method of adjacent diketone 深圳市有为化学技术有限公司 2018-01-09 CN claimed
US-7462443-B2 Leuco dye-containing coating compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-12-09 US claimed
WO-2005026274-A1 COATING COMPOSITIONS CONTAINING A LEUCO DYE-AND A DIARYLGUANIDINE DYE HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2005-03-24 WO claimed
US-20050053870-A1 Leuco dye-containing coating compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-03-10 US claimed
EP-0828182-B1 Storage-stable photoimageable compositions with improved leuco dye DU PONT (US) 2003-11-19 EP claimed
US-5744280-A MONOCHROME IMAGES;IMPROVED CONTRAST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-28 US claimed
US-5741621-A PHOTORESISTS, SOLDER MASKS, PRINTING PLATES, PROOFING FILM PRODUCTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-21 US claimed
EP-0747769-A2 Process for producing photoimageable films prepared from aqueous photoimageable liquid emulsions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-11 EP claimed
EP-0324481-B1 STORAGE STABLE PHOTOPOLYMERIZABLE COMPOSITION FOR REFRACTIVE INDEX IMAGING E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-05 EP claimed
US-5153100-A Hexaarylbisimidazole and-or p-dialkylaminophenyl carbonyl compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-06 US claimed
US-20260147277-A1 TRANSFER FILM, PATTERN FORMING METHOD, LAMINATE, AND SEMICONDUCTOR PACKAGE FUJIFILM CORPORATION (JP) 2026-05-28 US disclosed
EP-4291953-B1 IMPROVED BLEACHING XETOS AG (DE) 2026-04-15 EP disclosed
EP-4291587-B1 PHOTOPOLYMERIZABLE HOE COMPOSITION XETOS AG (DE) 2025-11-12 EP disclosed
US-20250282976-A1 CROSSLINKED POLYSILAZANE AND COMPOSITION COMPRISING THE SAME MERCK PATENT GMBH (DE) 2025-09-11 US disclosed
US-20250277122-A1 Photopolymerizable HOE Composition XETOS AG (DE) 2025-09-04 US disclosed
CN-1036083-A In photopolymerizable layer, form the method for reflection hologram DU PONT (US) 1989-10-04 CN disclosed
CN-1035004-A The refractive index imaging photopolymerization material of stable storage DU PONT (US) 1989-08-23 CN disclosed
EP-0324480-A2 Photopolymerizable compositions and elements for refractive index imaging E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP disclosed
EP-0324482-A2 Process of forming reflection holograms in photopolymerizable layers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP disclosed
US-4175964-A SUCCESSIVE SURFACE TREATMENT WITH AQUEOUS SOLUTIONS OF PHOSPHORIC ACID AND SILICIC ACID OR ITS SALTS FUJI PHOTO FILM CO., LTD. (JP) 1979-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260147277-A1 TRANSFER FILM, PATTERN FORMING METHOD, LAMINATE, AND SEMICONDUCTOR PACKAGE LCP1, PCNA, FDFT1 HSD11B1 2199/4885CYP2A6 1979/4885LMNA 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.