Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246422 | 0.93 | ROCK2 (0.49) | ROCK2ROCK1 | |
| SCHEMBL3246424 | 0.77 | CCR5 (0.43) | — | |
| SCHEMBL3247220 | 0.76 | ROCK2 (0.47) | ROCK2ROCK1CHEK1 | |
| SCHEMBL3246520 | 0.75 | ROCK2 (0.59) | ROCK2ROCK1 | |
| SCHEMBL3242878 | 0.74 | ROCK2 (0.58) | ROCK2ROCK1 | |
| SCHEMBL3246237 | 0.74 | ROCK2 (0.73) | ROCK2ROCK1 | |
| SCHEMBL3245955 | 0.71 | ROCK2 (0.48) | ROCK2ROCK1 | |
| SCHEMBL3241276 | 0.70 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL3252994 | 0.70 | ROCK2 (0.49) | ROCK2ROCK1 | |
| SCHEMBL3244390 | 0.70 | ROCK2 (0.50) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |