SCHEMBL324742

SCHEMBL324742

C=CCc1cc(C=C)ccn1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
XDH P47989 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28143036 0.98 ALDH1A1 (0.32) ALDH1A1TP53TDP1
SCHEMBL2622773 0.80 RECQL (0.34) ALDH1A1TP53TDP1TSHR
SCHEMBL321696 0.80 CYP1A2 (0.44) ALDH1A1TP53TDP1TSHR
SCHEMBL9301260 0.79 GABRA1 (0.39) ALDH1A1XDH
SCHEMBL2556929 0.79 XDH (0.45) ALDH1A1TP53XDHTSHR
Bromide SCHEMBL28155749 0.78 CYP1A2 (0.43) ALDH1A1TP53TDP1TSHR
Iodide SCHEMBL27088326 0.78 CYP1A2 (0.43) ALDH1A1TP53TDP1TSHR
SCHEMBL17259072 0.77 KDM4E (0.34) ALDH1A1TP53TDP1TSHR
SCHEMBL9764334 0.77 KDM4E (0.49) ALDH1A1TP53TDP1TSHR
SCHEMBL23139999 0.76 UHRF1 (0.45) ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104994938-A Filtration systems and membranes with enhanced flux and methods of making the same BASF SE 2015-10-21 CN claimed
CN-104853833-A FILTRATION SYSTEMS AND MEMBRANES WITH ENHANCED FLUX AND METHOD FOR THEIR PREPARATION BASF SE 2015-08-19 CN claimed
CN-104994938-A Filtration systems and membranes with enhanced flux and methods of making the same BASF SE 2015-10-21 CN disclosed
CN-104853833-A FILTRATION SYSTEMS AND MEMBRANES WITH ENHANCED FLUX AND METHOD FOR THEIR PREPARATION BASF SE 2015-08-19 CN disclosed
US-8664173-B2 Premoistened cleaning disposable substrate for leather and method of preserving a leather surface by contacting said surface with said substrate BASF SE (DE) 2014-03-04 US disclosed
US-8093199-B2 Premoistened cleaning disposable substrate and method of incorporation of a cleaning composition into said substrate BASF SE (DE) 2012-01-10 US disclosed
EP-1789525-B1 PREMOISTENED DISPOSABLE WIPE PROCTER & GAMBLE (US) 2011-11-23 EP disclosed
EP-2082021-B1 PREMOISTENED CLEANING DISPOSABLE SUBSTRATE BASF SE (DE) 2011-08-03 EP disclosed
US-7947086-B2 Method for cleaning household fabric-based surface with premoistened wipe THE PROCTER & GAMBLE COMPANY (US) 2011-05-24 US disclosed
EP-2082021-A1 PREMOISTENED CLEANING DISPOSABLE SUBSTRATE Ciba Holding Inc. (CH) 2009-07-29 EP disclosed
US-20080171683-A1 Premoistened cleaning disposable substrate for leather and method of preserving a leather surface by contacting said surface with said substrate BASF SE (DE) 2008-07-17 US disclosed
WO-2008059013-A1 PREMOISTENED CLEANING DISPOSABLE SUBSTRATE CIBA HOLDING INC. (CH) 2008-05-22 WO disclosed