Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953846 | 0.92 | MAPT (0.41) | GABRA1GABRB2EGFRKDM4EALDH1A1 | |
| SCHEMBL9403340 | 0.92 | PDE4A (0.36) | GABRA1GABRB2PDE4APDE4CPDE4D | |
| SCHEMBL11910285 | 0.85 | MAPT (0.33) | GABRA1GABRB2KDM4EALDH1A1MAPT | |
| SCHEMBL2556929 | 0.83 | XDH (0.45) | GABRA1GABRB2XDHKDM4EMEN1 | |
| SCHEMBL23139999 | 0.79 | UHRF1 (0.45) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL324742 | 0.79 | ALDH1A1 (0.33) | XDHALDH1A1 | |
| SCHEMBL3408217 | 0.79 | ASIC3 (0.37) | XDHMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2359581 | 0.79 | XDH (0.31) | XDH | |
| SCHEMBL629846 | 0.79 | XDH (0.38) | GABRA1GABRB2XDHKDM4EMEN1 | |
| SCHEMBL19860375 | 0.79 | HDAC8 (0.36) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336448-A | Light filters; reflectance mirrors | GENTEX CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |
| US-5294376-A | Rearview mirror | GENTEX CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5278693-A | Tinted solution-phase electrochromic devices | GENTEX CORPORATION (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0552012-A2 | Tinted solution-phase electrochromic devices | GENTEX CORPORATION (US) | 1993-07-21 | — | — | EP | disclosed |