Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442799 | 0.73 | DRD2 (0.55) | NOTUMLMNADRD2DRD4 | |
| SCHEMBL3243831 | 0.71 | KMT2A (0.44) | ALDH1A1NOTUMRAB9AMEN1KMT2A | |
| SCHEMBL28087158 | 0.70 | NOTUM (0.56) | ALDH1A1NOTUMCREBBPRAB9AMEN1 | |
| SCHEMBL8636626 | 0.69 | MEN1 (0.43) | ALDH1A1NOTUMRAB9AMEN1KMT2A | |
| SCHEMBL2827512 | 0.68 | NOTUM (0.60) | ALDH1A1NOTUMLMNADRD2DRD4 | |
| SCHEMBL29859758 | 0.68 | NOTUM (0.60) | ALDH1A1NOTUMLMNADRD2DRD4 | |
| SCHEMBL2827516 | 0.68 | NOTUM (0.60) | ALDH1A1NOTUMLMNADRD2DRD4 | |
| SCHEMBL5847721 | 0.68 | NOTUM (0.60) | ALDH1A1NOTUMLMNADRD2DRD4 | |
| SCHEMBL3246780 | 0.68 | CYP3A4 (0.41) | ALDH1A1NOTUMMEN1KMT2ALMNA | |
| SCHEMBL3246762 | 0.68 | CYP3A4 (0.41) | ALDH1A1NOTUMMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102204-B1 | NEW AMINOPYRROLO[1,2- A]INDOLE ET AMINOPYRIDAZINO[1,6-A]INDOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SERVIER LAB (FR) | 2010-05-05 | — | — | EP | disclosed |