Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL626059 | 1.00 | BBOX1 (0.49) | BBOX1ALDH1A1TSHRFGFR4KMT2A | |
| Acrylic Acid SCHEMBL7820172 | 0.98 | BBOX1 (0.47) | BBOX1ALDH1A1TSHRFGFR4KMT2A | |
| Acrylic Acid SCHEMBL1251542 | 0.96 | BBOX1 (0.49) | BBOX1ALDH1A1TSHRFGFR4KMT2A | |
| Acrylic Acid SCHEMBL578283 | 0.92 | BBOX1 (0.55) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Acrylamide SCHEMBL26087327 | 0.92 | ALDH1A1 (0.50) | BBOX1ALDH1A1TSHRFGFR4KMT2A | |
| Acrylamide SCHEMBL126949 | 0.92 | ALDH1A1 (0.50) | BBOX1ALDH1A1TSHRFGFR4KMT2A | |
| Acrylic Acid SCHEMBL11323113 | 0.92 | BBOX1 (0.55) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Acrylic Acid SCHEMBL4148615 | 0.90 | BBOX1 (0.53) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Acrylic Acid SCHEMBL2526435 | 0.90 | BBOX1 (0.57) | BBOX1ALDH1A1TSHRKMT2AATM | |
| Acrylamide SCHEMBL454374 | 0.90 | ALDH1A1 (0.52) | BBOX1ALDH1A1TSHRFGFR4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886661-B1 | Tinctorial composition containing a direct dye and an amphoteric polymer comprising units of acrylamide, dialkyldiallylammonium halide and vinyl carboxylic acid | OREAL (FR) | 2010-10-06 | — | — | EP | claimed |
| EP-1891933-B1 | Tinctorial composition containing an oxidation dye and an amphoteric polymer comprising units of acrylamide, dialkyldiallylammonium halide and vinyl carboxylic acid | OREAL (FR) | 2010-05-05 | — | — | EP | claimed |
| EP-1889605-B1 | Tinctorial composition containing a direct dye and an amphoteric polymer comprising units of acrylamide, dialkyldiallylammonium halide and vinyl carboxylic acid | OREAL (FR) | 2009-12-09 | — | — | EP | claimed |
| US-7559957-B2 | Dyeing composition comprising at least one oxidation dye and at least one polymer comprising an acrylamide, dialkyldiallylammonium halide and vinylcarboxylic acid, with a high content of acrylamide | L'OREAL S.A. (FR) | 2009-07-14 | — | — | US | claimed |
| US-7559958-B2 | Dyeing composition comprising at least one oxidation dye and at least one amphoteric polymer comprising acrylamide, dialkyldiallylammonium halide and a high level of vinylcarboxylic acid | L'OREAL S.A. (FR) | 2009-07-14 | — | — | US | claimed |
| US-20080066772-A1 | Dyeing composition comprising at least one oxidation dye and at least one polymer comprising an acrylamide, dialkyldiallylammonium halide and vinylcarboxylic acid, with a high content of acrylamide | L'OREAL S.A. (FR) | 2008-03-20 | — | — | US | claimed |
| US-20080034507-A1 | Dyeing composition comprising at least one oxidation dye and at least one amphoteric polymer comprising acrylamide, dialkyldiallylammonium halide and a high level of vinylcarboxylic acid | L'OREAL S.A. (FR) | 2008-02-14 | — | — | US | claimed |
| CN-116940331-A | Cleansing compositions providing enhanced salicylic acid deposition for acne treatment | 欧莱雅 | 2023-10-24 | — | — | CN | disclosed |
| CN-111295178-A | Method for improving color durability of artificially colored hair | 莱雅公司 | 2020-06-16 | — | — | CN | disclosed |
| US-7559957-B2 | Dyeing composition comprising at least one oxidation dye and at least one polymer comprising an acrylamide, dialkyldiallylammonium halide and vinylcarboxylic acid, with a high content of acrylamide | L'OREAL S.A. (FR) | 2009-07-14 | — | — | US | disclosed |
| US-7559958-B2 | Dyeing composition comprising at least one oxidation dye and at least one amphoteric polymer comprising acrylamide, dialkyldiallylammonium halide and a high level of vinylcarboxylic acid | L'OREAL S.A. (FR) | 2009-07-14 | — | — | US | disclosed |
| US-7364594-B2 | Dyeing composition for keratinous fibres comprising an associative polymer and a polymer with acrylamide units, dialkyldiallylammonium halide, and vinylic carboxylic acid | L'OREAL S.A. (FR) | 2008-04-29 | — | — | US | disclosed |
| US-20080066772-A1 | Dyeing composition comprising at least one oxidation dye and at least one polymer comprising an acrylamide, dialkyldiallylammonium halide and vinylcarboxylic acid, with a high content of acrylamide | L'OREAL S.A. (FR) | 2008-03-20 | — | — | US | disclosed |
| US-5338541-A | Dual cationic terpolymers providing superior conditioning properties in hair, skin and nail care products | CALGON CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| US-5296218-A | Containing acrylamide, diallyldimethylammonium chloride, acrylic acid monomers | CALGON CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| US-5275809-A | Nonionic acrylamide monomer; cationic dimethydiallylammonium chloride monomer; anionic 2-acrylamido-2-methylpropane sulfonic acid monomer | CALGON CORPORATION (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0522756-A1 | Ampholyte terpolymers providing superior conditioning properties in skin and nail care products | Calgon Corporation (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0522755-A1 | Ampholyte terpolymers providing superior conditioning properties in shampoos and other hair care products | Calgon Corporation (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0521666-A1 | Ampholyte terpolymers providing superior conditioning properties in shampoos and other hair care products | Calgon Corporation (US) | 1993-01-07 | — | — | EP | disclosed |
| EP-0521665-A1 | Ampholyte terpolymers providing superior conditioning properties in shampoos and other hair care products | Calgon Corporation (US) | 1993-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080066772-A1 | Dyeing composition comprising at least one oxidation dye and at least one polymer comprising an acrylamide, dialkyldiallylammonium halide and vinylcarboxylic acid, with a high content of acrylamide | KRT18, GFER, DDR1 | BBOX1 1740/4885ALDH1A1 56/4885TSHR 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.