SCHEMBL3248276

SCHEMBL3248276

C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)CC4)[nH]3.[MgH2]

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.34
▸ STAT1 P42224 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820256 0.98 STAT3 (0.35) STAT3STAT1
SCHEMBL25612 0.98 STAT3 (0.35) STAT3STAT1
SCHEMBL1684236 0.96 STAT3 (0.34) STAT3STAT1
Hydrochloric Acid SCHEMBL8403409 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL670040 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL6411978 0.96 STAT3 (0.37) STAT3STAT1
SCHEMBL98554 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL6418524 0.96 STAT3 (0.37) STAT3STAT1
SCHEMBL13584886 0.94 STAT3 (0.33) STAT3STAT1
Ethylene SCHEMBL18262006 0.93 STAT3 (0.33) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190307893-A1 NANOVESICLES WITH PORPHYRIN-LIPID CONJUGATE CORE UNIVERSITY HEALTH NETWORK (CA) 2019-10-10 — — US disclosed
WO-2017156616-A1 NANOVESICLES COMPRISING PORPHYRIN-LIPID CONJUGATES EXHIBITING ORDERED ASSEMBLY AND BATHOCHROMIC SHIFTS UNIVERSITY HEALTH NETWORK (CA) 2017-09-21 — — WO disclosed
US-9417245-B2 Porphyrinic compounds for use in flow cytometry NORTH CAROLINA STATE UNIVERSITY (US) 2016-08-16 — — US disclosed
US-20150153350-A1 PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-06-04 — — US disclosed
US-8980565-B2 Porphyrinic compounds for use in flow cytometry NORTH CAROLINA STATE UNIVERSITY (US) 2015-03-17 — — US disclosed
US-8546088-B2 Porphyrinic compounds for use in flow cytometry NORTH CAROLINA STATE UNIVERSITY (US) 2013-10-01 — — US disclosed
US-20120245508-A1 SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2012-09-27 — — US disclosed
US-20120244551-A1 PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-09-27 — — US disclosed
US-8207329-B2 Synthesis of chlorins and phorbines with enhanced red spectral features NORTH CAROLINA STATE UNIVERSITY (US) 2012-06-26 — — US disclosed
US-8187824-B2 Porphyrinic compounds for use in flow cytometry NORTH CAROLINA STATE UNIVERSITY (US) 2012-05-29 — — US disclosed
US-20090075295-A1 PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-03-19 — — US disclosed
WO-2007064841-A2 PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY NORTH CAROLINA STATE UNIVERSITY (US) 2007-06-07 — — WO disclosed
WO-2007064842-A2 SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES NORTH CAROLINA STATE UNIVERSITY (US) 2007-06-07 — — WO disclosed
EP-1117666-B1 PROCESS FOR THE PREPARATION OF CORROLES AND SEVERAL SUCH NEW COMPOUNDS, INCLUDING CHIRAL DERIVATIVES, AND THE USE THEREOF TECHNION RES & DEV FOUNDATION (IL) 2004-12-01 — — EP disclosed
EP-1469001-A1 Corroles, including chiral derivatives and the use thereof Technion Research & Development Foundation Limited (IL) 2004-10-20 — — EP disclosed
US-6541628-B1 Solvent-free condensation of an aldehyde with a pyrrole derivative to form corroles, salts or complexes TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2003-04-01 — — US disclosed
CN-1085211-C Synthetic metal-substituted bacteriochlorophyll derivs. and use thereof YEDA RES & DEV (IL) 2002-05-22 — — CN disclosed
EP-1117666-A2 PROCESS FOR THE PREPARATION OF CORROLES AND SEVERAL SUCH NEW COMPOUNDS, INCLUDING CHIRAL DERIVATIVES, AND THE USE THEREOF Technion Research & Development Foundation Limited (IL) 2001-07-25 — — EP disclosed
WO-2000018771-A2 PROCESS FOR THE PREPARATION OF CORROLES AND SEVERAL SUCH NEW COMPOUNDS, INCLUDING CHIRAL DERIVATIVES, AND THE USE THEREOF TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2000-04-06 — — WO disclosed
CN-1207741-A Synthetic metal substituted bacteriochlorophyll derivatives and their use YEDA RES & DEV (IL) 1999-02-10 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190307893-A1 NANOVESICLES WITH PORPHYRIN-LIPID CONJUGATE CORE PHOSPHO1, PCYT1A, CLTB STAT3 4330/4885STAT1 4170/4885
US-20120245508-A1 SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES CRY1, CRY2, QDPR STAT3 3528/4885STAT1 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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