SCHEMBL98554

SCHEMBL98554

C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)CC4)[nH]3.[SnH2]

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.34
▸ STAT1 P42224 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820256 0.98 STAT3 (0.35) STAT3STAT1
SCHEMBL25612 0.98 STAT3 (0.35) STAT3STAT1
Hydrochloric Acid SCHEMBL8403409 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL670040 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL1684236 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL15874559 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL6411978 0.96 STAT3 (0.37) STAT3STAT1
SCHEMBL6418524 0.96 STAT3 (0.37) STAT3STAT1
SCHEMBL3248276 0.96 STAT3 (0.34) STAT3STAT1
SCHEMBL13584886 0.94 STAT3 (0.33) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094292-A1 Photoactivatable Antimicrobial Agents And Therapeutic And Diagnostic Methods Of Using Same THE GENERAL HOSPITAL CORPORATION 2018-04-05 — — US claimed
US-20160073634-A1 BETA-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2016-03-17 — — US claimed
US-8703427-B2 Biological materials and uses thereof PHOTOBIOTICS LIMITED (GB) 2014-04-22 — — US claimed
WO-2013192521-A1 β-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION THE GENERAL HOSPITAL CORPORATION (US) 2013-12-27 — — WO claimed
EP-2285381-A2 PHOTOACTIVATABLE ANTIMICROBIAL AGENTS AND THERAPEUTIC AND DIAGNOSTIC METHODS OF USING SAME The General Hospital Corporation (US) 2011-02-23 — — EP claimed
US-20100016208-A1 PHOTOACTIVATABLE ANTIMICROBIAL AGENTS THE GENERAL HOSPITAL CORPORATION (US) 2010-01-21 — — US claimed
US-20090304803-A1 Compositions and methods relating to target-specific photodynamic therapy THE GENERAL HOSPITAL CORPORATION (US) 2009-12-10 — — US claimed
WO-2009137062-A2 PHOTOACTIVATABLE ANTIMICROBIAL AGENTS AND THERAPEUTIC AND DIAGNOSTIC METHODS OF USING SAME THE GENERAL HOSPITAL CORPORATION (US) 2009-11-12 — — WO claimed
EP-1962833-A2 PHOTOACTIVATABLE ANTIMICROBIAL AGENTS THE GENERAL HOSPITAL CORPORATION (US) 2008-09-03 — — EP claimed
WO-2007059226-A2 PHOTOACTIVATABLE ANTIMICROBIAL AGENTS THE GENERAL HOSPITAL CORPORATION (US) 2007-05-24 — — WO claimed
WO-2006133271-A2 COMPOSITIONS AND METHODS RELATING TO TARGET-SPECIFIC PHOTODYNAMIC THERAPY THE GENERAL HOSPITAL CORPORATION (US) 2006-12-14 — — WO claimed
US-20020197262-A1 Photoimmunotherapies for cancer using photosensitizer immunoconjugates and combination therapies NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-12-26 — — US claimed
WO-2002100326-A2 PHOTOIMMUNOTHERAPIES FOR CANCER USING PHOTOSENSITIZER IMMUNOCONJUGATES AND COMBINATION THERAPIES THE GENERAL HOSPITAL CORPORATION (US) 2002-12-19 — — WO claimed
US-11998266-B2 Intravascular energy delivery OTSUKA MEDICAL DEVICES CO., LTD (JP) 2024-06-04 — — US disclosed
US-20240139540-A1 LIGHT-BASED SYSTEM AND METHOD FOR SHAPING AND TREATING HAIR THE GENERAL HOSPITAL CORPORATION (US) 2024-05-02 — — US disclosed
US-20240033347-A1 ONCOLYTIC VACCINIA VIRUSES AND RECOMBINANT VIRUSES AND METHODS OF USE THEREOF VIROMISSILE, INC. (US) 2024-02-01 — — US disclosed
WO-2003003975-A2 DETECTION AND THERAPY OF VULNERABLE PLAQUE WITH PHOTODYNAMIC COMPOUNDS THE GENERAL HOSPITAL CORPORATION (US) 2003-01-16 — — WO disclosed
US-20020197262-A1 Photoimmunotherapies for cancer using photosensitizer immunoconjugates and combination therapies NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-12-26 — — US disclosed
WO-2002100326-A2 PHOTOIMMUNOTHERAPIES FOR CANCER USING PHOTOSENSITIZER IMMUNOCONJUGATES AND COMBINATION THERAPIES THE GENERAL HOSPITAL CORPORATION (US) 2002-12-19 — — WO disclosed
US-20020187935-A1 Photochemical tissue bonding AURA MEDSYSTEMS, INC. 2002-12-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160073634-A1 BETA-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION DDT, BCHE, GUSB STAT3 4740/4885STAT1 4162/4885
US-20100016208-A1 PHOTOACTIVATABLE ANTIMICROBIAL AGENTS CRY1, HMBS, PPOX STAT3 1242/4885STAT1 268/4885
US-20180094292-A1 Photoactivatable Antimicrobial Agents And Therapeutic And Diagnostic Methods Of Using Same HMBS, GUSB, LCT STAT3 4491/4885STAT1 3529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback