Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241840 | 0.89 | KDM4E (0.41) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3250557 | 0.88 | MAPT (0.41) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3249059 | 0.88 | MAPT (0.47) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3253968 | 0.88 | PKM (0.49) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3250591 | 0.88 | PARG (0.48) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3254878 | 0.87 | PKM (0.52) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3251387 | 0.87 | POLB (0.40) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3250099 | 0.87 | POLB (0.47) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3249858 | 0.87 | HSD17B10 (0.42) | HSD17B10KDM4EMEN1KMT2APOLB | |
| SCHEMBL3243020 | 0.87 | PKM (0.48) | HSD17B10KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |