Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241840 | 0.91 | KDM4E (0.41) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3247431 | 0.88 | MAPT (0.48) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3248591 | 0.88 | TAS2R14 (0.43) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3252092 | 0.86 | KMT2A (0.50) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3255332 | 0.85 | ADORA3 (0.40) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3243041 | 0.85 | WEE1 (0.38) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3255978 | 0.85 | FEN1 (0.39) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3250430 | 0.85 | HSD17B10 (0.45) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3250743 | 0.84 | KDM4E (0.39) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL3253160 | 0.84 | MEN1 (0.51) | MAPTKDM4EMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |