Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250557 | 0.91 | MAPT (0.41) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3247431 | 0.89 | MAPT (0.48) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3248591 | 0.89 | TAS2R14 (0.43) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3252092 | 0.89 | KMT2A (0.50) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3253160 | 0.87 | MEN1 (0.51) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3243041 | 0.86 | WEE1 (0.38) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3251774 | 0.86 | CASP3 (0.52) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3255978 | 0.86 | FEN1 (0.39) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3249059 | 0.85 | MAPT (0.47) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL3250591 | 0.85 | PARG (0.48) | KDM4EMEN1KMT2AHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |