Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033357 | 0.82 | FDPS (0.42) | HPGDHDAC1ENPP2ALDH1A1MAPT | |
| SCHEMBL10910029 | 0.82 | ESR1 (0.42) | HPGDENPP2LMNAALDH1A1 | |
| SCHEMBL5210171 | 0.81 | HPGD (0.61) | HPGDLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19018942 | 0.80 | HPGD (0.36) | HPGDHDAC1ENPP2SMN1; SMN2 | |
| SCHEMBL28741620 | 0.77 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1MAPTRARB | |
| SCHEMBL10397175 | 0.77 | CYP2A6 (0.55) | HRH3HTTALDH1A1MAPT | |
| SCHEMBL2038554 | 0.76 | LOXL2 (0.50) | ALDH1A1MAPT | |
| SCHEMBL8220530 | 0.76 | PLA2G10 (0.47) | HDAC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10945197 | 0.75 | CYP2C19 (0.45) | HPGDENPP2TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3122235 | 0.74 | CYP1A2 (0.41) | HPGDHDAC1BDKRB2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645552-B1 | Electroluminescent devices made with double-spiro organic compounds | LG CHEMICAL LTD (KR) | 2010-05-05 | — | — | EP | disclosed |
| EP-1294823-B1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG CHEMICAL LTD (KR) | 2006-12-13 | — | — | EP | disclosed |
| EP-1645552-A1 | Double-spiro organic compounds and electroluminescent devices | LG Chem, Ltd. (KR) | 2006-04-12 | — | — | EP | disclosed |
| US-6998487-B2 | Double-spiro organic compounds and organic electroluminescent devices using the same | LG CHEM, LTD. (KR) | 2006-02-14 | — | — | US | disclosed |
| US-6984462-B2 | Organic electroluminescent devices using double-spiro organic compounds | LG CHEM, LTD. (KR) | 2006-01-10 | — | — | US | disclosed |
| US-20040170863-A1 | Organic electroluminescent devices using double-spiro organic compounds | LG CHEM, LTD. (KR) | 2004-09-02 | — | — | US | disclosed |
| US-20040023060-A1 | Double-spiro organic compounds and organic electroluminescent devices using the same | LG CHEM, LTD. (KR) | 2004-02-05 | — | — | US | disclosed |
| EP-1294823-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG Chem, Ltd. (KR) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002088274-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG CHEM, LTD. (KR) | 2002-11-07 | — | — | WO | disclosed |