Pyrimorph

Pyrimorph

SCHEMBL324973

CC(C)(C)c1ccc(/C(=C\C(=O)N2CCOCC2)c2ccnc(Cl)c2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.49
NPC1 O15118 3/20 0.49
ALDH1A1 P00352 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HPGD P15428 2/20 0.49
TRPV1 Q8NER1 2/20 0.42
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
POLB P06746 1/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PHGDH O43175 1/20 0.40
BTK Q06187 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimorph SCHEMBL29366446 1.00 RAB9A (0.49) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
Pyrimorph SCHEMBL325300 1.00 RAB9A (0.49) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
Pyrimorph SCHEMBL29368725 1.00 RAB9A (0.49) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
Pyrimorph SCHEMBL324974 1.00 RAB9A (0.49) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
SCHEMBL20268480 0.82 HSP90AA1 (0.42) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
SCHEMBL14167676 0.82 TP53 (0.40) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
SCHEMBL14167677 0.82 TP53 (0.40) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
SCHEMBL15942409 0.81 MEN1 (0.40) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
SCHEMBL9937937 0.81 MEN1 (0.40) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD
SCHEMBL14690854 0.81 MEN1 (0.40) RAB9ANPC1ALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384016-B1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AG (DE) 2025-09-03 EP claimed
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2024-11-07 US claimed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 CN claimed
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 US claimed
EP-4250926-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI Industries Ltd. (IN) 2023-10-04 EP claimed
CN-116801720-A Novel agrochemical compositions comprising 3-substituted benzamidine compounds and uses thereof 皮埃企业有限公司 2023-09-22 CN claimed
EP-4188094-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING PYRAZOLOPYRIDINE ANTHRANILAMIDE COMPOUND, OXIDES OR SALTS THEREOF PI Industries Ltd. (IN) 2023-06-07 EP claimed
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN claimed
US-20230165252-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2023-06-01 US claimed
EP-4175476-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF PI Industries Ltd. (IN) 2023-05-10 EP claimed
WO-2014037314-A2 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO claimed
WO-2014029747-A1 COMPOSITION COMPRISING A PESTICIDAL TERPENE MIXTURE AND A BIOLOGICAL CONTROL AGENT BAYER CROPSCIENCE AG (DE) 2014-02-27 WO claimed
WO-2014020109-A1 COMPOSITION COMPRISING A PESTICIDAL TERPENE MIXTURE AND A FUNGICIDE BAYER CROPSCIENCE AG (DE) 2014-02-06 WO claimed
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-02-06 US claimed
WO-2014019983-A1 COMPOSITIONS COMPRISING A PESTICIDAL TERPENE MIXTURE AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2014-02-06 WO claimed
WO-2013178649-A1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE FROM THE GROUP CONSISTING OF INHIBITORS OF THE RESPIRATORY CHAIN AT COMPLEX I OR II. BAYER CROPSCIENCE AG (DE) 2013-12-05 WO claimed
EP-2651209-A2 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF Syngenta Participations AG (CH) 2013-10-23 EP claimed
EP-2606726-A1 N-Arylamidine-substituted trifluoroethylsulfide derivatives as acaricides and insecticides Bayer CropScience AG (DE) 2013-06-26 EP claimed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012082548-A2 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX RAB9A 2628/4885NPC1 2222/4885ALDH1A1 2558/4885
US-20230165252-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX RAB9A 2628/4885NPC1 2222/4885ALDH1A1 2558/4885
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE DDT, TH, HPD RAB9A 4014/4885NPC1 4076/4885ALDH1A1 517/4885
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND AADAC, TUBA3C, NAT1 RAB9A 3615/4885NPC1 1215/4885ALDH1A1 1039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.