Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143202 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL27399229 | 0.83 | MAPT (0.43) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL471095 | 0.82 | MAPT (0.63) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL213877 | 0.82 | PTPN7 (0.51) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL111211 | 0.82 | MAPT (0.49) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL29392600 | 0.82 | MAPT (0.49) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL5276459 | 0.81 | NPC1 (0.64) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL470841 | 0.81 | MAPT (0.47) | SMN1; SMN2MAPTPOLBALDH1A1SIRT5 | |
| SCHEMBL15064772 | 0.81 | MAPT (0.48) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| Hydrochloric Acid SCHEMBL9760985 | 0.81 | MAPT (0.48) | SMN1; SMN2NPC1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666095-B1 | Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | OREAL (FR) | 2010-05-19 | — | — | EP | claimed |
| US-7452386-B2 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2008-11-18 | — | — | US | claimed |
| US-20060191080-A1 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | claimed |
| EP-1666095-A1 | Composition for simultanesou colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | Societe L'Oreal S.A. (FR) | 2006-06-07 | — | — | EP | claimed |
| EP-1666095-B1 | Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | OREAL (FR) | 2010-05-19 | — | — | EP | disclosed |
| US-7452386-B2 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2008-11-18 | — | — | US | disclosed |
| US-20060191080-A1 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | disclosed |
| EP-1666095-A1 | Composition for simultanesou colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | Societe L'Oreal S.A. (FR) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060191080-A1 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | KRT18, NOX4, NOX5 | SMN1; SMN2 1896/4885NPC1 4239/4885RAB9A 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.