Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242733 | 0.85 | GRIN1 (0.50) | GRIN1GRIN2B | |
| SCHEMBL13521762 | 0.85 | TAAR1 (0.41) | OPRM1OPRK1 | |
| SCHEMBL3249233 | 0.83 | GRIN2B (0.61) | GRIN1GRIN2B | |
| SCHEMBL3245322 | 0.81 | GRIN1 (0.51) | GRIN1GRIN2B | |
| SCHEMBL3252351 | 0.81 | GRIN2B (0.52) | GRIN1GRIN2B | |
| SCHEMBL3245549 | 0.79 | GRIN1 (0.46) | GRIN1GRIN2B | |
| SCHEMBL3236751 | 0.79 | GRIN1 (0.46) | GRIN1GRIN2B | |
| SCHEMBL3252047 | 0.77 | GRIN1 (0.46) | ROCK1GRIN1GRIN2B | |
| SCHEMBL3256125 | 0.75 | GRIN2B (0.55) | GRIN1GRIN2B | |
| SCHEMBL3244881 | 0.74 | ROCK1 (0.40) | ROCK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |