Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 10/20 | 0.49 |
| ▸ | CES2 | O00748 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 3/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260547 | 0.90 | CES1 (0.46) | CES1CES2LMNASRCKMT2A | |
| SCHEMBL868096 | 0.86 | CES1 (0.51) | CES1CES2LMNASRCCYP1A2 | |
| SCHEMBL10880596 | 0.83 | CES1 (0.45) | CES1CES2LMNASRCCYP3A4 | |
| SCHEMBL8585923 | 0.83 | KIF11 (0.46) | CES1CES2LMNASRCSCN1A | |
| SCHEMBL7945147 | 0.81 | CES1 (0.49) | CES1CES2LMNASRCCYP3A4 | |
| SCHEMBL1255415 | 0.80 | LMNA (0.50) | CES1CES2LMNASRCSCN1A | |
| SCHEMBL476563 | 0.79 | CES1 (0.47) | CES1CES2LMNASRCCYP1A2 | |
| SCHEMBL7914713 | 0.78 | CES1 (0.44) | CES1CES2LMNATSHRTDP1 | |
| SCHEMBL10456740 | 0.78 | CES1 (0.59) | CES1CES2LMNASRCCYP1A2 | |
| SCHEMBL3266513 | 0.77 | PTPN1 (0.50) | CES1CES2LMNASRCSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549689-B1 | A HYDROGEL | COLOPLAST AS (DK) | 2010-05-26 | — | — | EP | disclosed |
| US-7511083-B2 | hydrophilic saturated polymers activated by the photodecomposition of peroxidisulphate to create free radicals through hydrogen abstraction and subsequent crosslinking by graft copolymerisation under UV; PVA, polysaccharides, polyvinylpyrrolidone; PEG Acrylates: medical dressings, tissue engineering | COLOPLAST A/S (DK) | 2009-03-31 | — | — | US | disclosed |
| US-20060052478-A1 | hydrophilic saturated polymers activated by the photodecomposition of peroxidisulphate to create free radicals through hydrogen abstraction and subsequent crosslinking by graft copolymerisation under UV; PVA, polysaccharides, polyvinylpyrrolidone; PEG Acrylates: medical dressings, tissue engineering | COLOPLAST A/S (DK) | 2006-03-09 | — | — | US | disclosed |
| EP-1549689-A1 | A HYDROGEL | COLOPLAST A/S (DK) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004031253-A1 | A HYDROGEL | COLOPLAST A/S (DK) | 2004-04-15 | — | — | WO | disclosed |
| US-5005287-A | Coating with water soluble polyvinylpyrrolidone | WILKINSON SWORD GMBH (DE) | 1991-04-09 | — | — | US | disclosed |