Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | RASGRP3 | Q8IV61 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252121 | 1.00 | MAPT (0.39) | MAPTMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL3240716 | 0.88 | ALDH1A1 (0.38) | MEN1KMT2ANPC1APPALDH1A1 | |
| SCHEMBL3254651 | 0.88 | ALDH1A1 (0.38) | MEN1KMT2ANPC1APPALDH1A1 | |
| SCHEMBL3253754 | 0.85 | MEN1 (0.41) | MAPTMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL3253634 | 0.85 | MEN1 (0.41) | MAPTMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL3248509 | 0.85 | NPSR1 (0.43) | MAPTMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL3249744 | 0.85 | NPSR1 (0.43) | MAPTMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL3251936 | 0.83 | APP (0.39) | MAPTMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL12311091 | 0.83 | APP (0.39) | MAPTMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL3248731 | 0.83 | APP (0.39) | MAPTMEN1KMT2ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747774-B1 | Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres | OREAL (FR) | 2010-05-05 | — | — | EP | claimed |
| US-7585332-B2 | Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device | L'OREAL S.A. (FR) | 2009-09-08 | — | — | US | claimed |
| US-7399319-B2 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-07-15 | — | — | US | claimed |
| US-7585332-B2 | Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device | L'OREAL S.A. (FR) | 2009-09-08 | — | — | US | disclosed |
| US-7527654-B2 | Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process | L'OREAL S.A. (FR) | 2009-05-05 | — | — | US | disclosed |
| US-20090019645-A1 | UNKNOWN | L'OREAL S.A. (FR) | 2009-01-22 | — | — | US | disclosed |
| US-20080189878-A1 | Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process | L'OREAL S.A. (FR) | 2008-08-14 | — | — | US | disclosed |
| US-7399319-B2 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-07-15 | — | — | US | disclosed |
| US-20070174977-A1 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090019645-A1 | UNKNOWN | KRT18, SQOR, MT-ND5 | MAPT 1040/4885MEN1 3959/4885KMT2A 1588/4885 |
| US-20080189878-A1 | Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process | KRT18, INHA, IK | MAPT 854/4885MEN1 2999/4885KMT2A 809/4885 |
| US-20070174977-A1 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | KRT18, INHA, IK | MAPT 1182/4885MEN1 3368/4885KMT2A 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.