Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246422 | 0.79 | ROCK2 (0.49) | — | |
| SCHEMBL4465185 | 0.64 | MEN1 (0.55) | CCR5SIGMAR1ACHEKMT2A | |
| SCHEMBL31572354 | 0.61 | ALDH1A1 (0.52) | HSD11B1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19580057 | 0.60 | HTR7 (0.52) | OPRM1SIGMAR1OPRD1KMT2A | |
| SCHEMBL27150592 | 0.59 | HSD11B1 (0.57) | HSD11B1ALDH1A1 | |
| SCHEMBL27150593 | 0.59 | HSD11B1 (0.57) | HSD11B1ALDH1A1 | |
| SCHEMBL3245955 | 0.59 | ROCK2 (0.48) | — | |
| SCHEMBL12311314 | 0.59 | PAX8 (0.49) | CHRM5CHRM1CHRM3CHRM2ALDH1A1 | |
| SCHEMBL433443 | 0.58 | HRH3 (0.43) | OPRK1PTGIROPRM1SIGMAR1OPRD1 | |
| SCHEMBL25920399 | 0.58 | CHRM2 (0.43) | CHRM1CHRM3CHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |