SCHEMBL3255039

SCHEMBL3255039

COC(=O)C(OC)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.64
ALDH1A1 P00352 5/20 0.56
GAA P10253 2/20 0.56
L3MBTL1 Q9Y468 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
LMNA P02545 2/20 0.51
PKM P14618 1/20 0.51
KDM4E B2RXH2 1/20 0.51
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3255043 1.00 KMT2A (0.64) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL13848573 1.00 KMT2A (0.64) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL4059785 0.88 KMT2A (0.53) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL10903458 0.84 KMT2A (0.50) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL7701652 0.84 KMT2A (0.60) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL1521123 0.84 KMT2A (0.60) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL7701655 0.84 KMT2A (0.60) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL9539620 0.83 ALDH1A1 (0.54) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL155984 0.83 ALDH1A1 (0.54) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2
SCHEMBL103235 0.83 ALDH1A1 (0.54) KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117930588-A Photosensitive glue solution and preparation method and application thereof 广东拓谱电子科技有限公司 2024-04-26 CN claimed
CN-116948543-B Light shaping protective film for curved screen and preparation method thereof 江西昊泽光学膜科技有限公司 2024-02-13 CN claimed
CN-116948543-A Light shaping protective film for curved screen and preparation method thereof 江西昊泽光学膜科技有限公司 2023-10-27 CN claimed
CN-108929226-B Method for preparing benzoyl formate derivative 广东工业大学 2021-05-28 CN claimed
CN-109096425-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-108929226-A A method of preparing benzoyl formic acid ester derivant 广东工业大学 2018-12-04 CN claimed
CN-103172511-A Synthetic method of (R)-(-)-alpha-methoxyphenylacetic acid UNIV SHENYANG PHARMACEUTICAL 2013-06-26 CN claimed
EP-3541802-B1 ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AMGEN INC (US) 2025-01-01 EP disclosed
CN-118580164-A Preparation method of sulfoxide derivative 华侨大学 2024-09-03 CN disclosed
CN-117930588-A Photosensitive glue solution and preparation method and application thereof 广东拓谱电子科技有限公司 2024-04-26 CN disclosed
CN-116948543-B Light shaping protective film for curved screen and preparation method thereof 江西昊泽光学膜科技有限公司 2024-02-13 CN disclosed
CN-116948543-A Light shaping protective film for curved screen and preparation method thereof 江西昊泽光学膜科技有限公司 2023-10-27 CN disclosed
CN-116854582-A Preparation method of enantiomerically pure alpha-methoxyphenylacetic acid 泰州葛林美克医药科技有限公司 2023-10-10 CN disclosed
WO-2005014555-A1 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS AVENTIS PHARMACEUTICALS INC. (US) 2005-02-17 WO disclosed
US-20050026916-A1 Heterocyclic compounds as P2X7 ion channel blockers AVENTIS PHARMACEUTICALS INC. (US) 2005-02-03 US disclosed
WO-1998031697-A1 ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF SANKYO COMPANY, LIMITED (JP) 1998-07-23 WO disclosed
US-5389659-A Hypotensive agents GLAXO GROUP LIMITED (GB) 1995-02-14 US disclosed
WO-1993005025-A1 C-LINKED PYRAZOLE DERIVATIVES GLAXO GROUP LIMITED (GB) 1993-03-18 WO disclosed
US-5063225-A Antiarrhythmia ROUSSEL UCLAF (FR) 1991-11-05 US disclosed
EP-0446062-A1 C-Linked pyrazole derivatives GLAXO GROUP LIMITED (GB) 1991-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026916-A1 Heterocyclic compounds as P2X7 ion channel blockers P2RX3, P2RX2, P2RX5 KMT2A 3229/4885ALDH1A1 1913/4885GAA 4232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.