SCHEMBL3255153

SCHEMBL3255153

Cc1cc(C)c(CBr)c(C)c1CBr

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.44
PGK2 P07205 1/20 0.44
SLC11A2 P49281 1/20 0.40
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTR1D P28221 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7945820 0.89 PGK1 (0.37) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL13306021 0.88 PGK1 (0.38) PGK1PGK2SLC11A2
SCHEMBL29126141 0.83 CA1 (0.39) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL11217789 0.82 CYP3A4 (0.35) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL28337198 0.78 CYP3A4 (0.39) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL11416603 0.77
SCHEMBL258395 0.77
SCHEMBL893003 0.77 ALDH1A1 (0.41) PGK1PGK2CYP3A4TSHRHTR1D
SCHEMBL585059 0.77 HRH3 (0.40) TSHRMAPK1HTR1D
SCHEMBL18280483 0.76 CYP3A4 (0.41) PGK1PGK2CYP3A4MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060915-A2 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME Mologic Limited (GB) 2016-08-31 EP claimed
WO-2015059487-A2 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME MOLOGIC LIMITED (GB) 2015-04-30 WO claimed
US-12320804-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2025-06-03 US disclosed
US-20250157661-A1 MONITORING INFLAMMATION STATUS MOLOGIC LIMITED (GB) 2025-05-15 US disclosed
WO-2025094673-A1 VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, FILM WITH RESIN, METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD 住友化学株式会社 2025-05-08 WO disclosed
US-11953506-B2 Monitoring inflammation status MOLOGIC LIMITED (GB) 2024-04-09 US disclosed
EP-3928100-B1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LTD (GB) 2023-03-22 EP disclosed
US-20220120760-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LIMITED (GB) 2022-04-21 US disclosed
US-20220120760-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LIMITED (GB) 2022-04-21 US disclosed
EP-3928100-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION Mologic Limited (GB) 2021-12-29 EP disclosed
US-10866236-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2020-12-15 US disclosed
US-20070032578-A1 Curable liquid compositions containing bisoxazoline HENKEL KGAA (DE) 2007-02-08 US disclosed
US-20070032578-A1 Curable liquid compositions containing bisoxazoline HENKEL KGAA (DE) 2007-02-08 US disclosed
EP-1730117-A2 THIOUREA COMPOSITIONS AND USES THEREOF The University of Hong Kong (CN) 2006-12-13 EP disclosed
EP-1716215-A1 CURABLE LIQUID COMPOSITIONS CONTAINING BISOXAZOLINE National Starch and Chemical Investment Holding Corporation (US) 2006-11-02 EP disclosed
WO-2005091697-A2 THIOUREA COMPOSITIONS AND USES THEREOF THE UNIVERSITY OF HONG KONG (CN) 2005-10-06 WO disclosed
US-20050215783-A1 Thiourea compositions and uses thereof UNIVERSITY OF HONG KONG, THE (HK) 2005-09-29 US disclosed
WO-2005085384-A1 CURABLE LIQUID COMPOSITIONS CONTAINING BISOXAZOLINE NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING COPORATION (US) 2005-09-15 WO disclosed
US-6252009-B1 CROSSLINKING ACRYLONITRILE WITH DIISOCYANATE THE GOODYEAR TIRE & RUBBER COMPANY 2001-06-26 US disclosed
EP-0903338-A2 Synthesis of stable nitrile oxide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215783-A1 Thiourea compositions and uses thereof DDT, ITK, DTYMK PGK1 681/4885PGK2 733/4885SLC11A2 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.