Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17648045 | 0.97 | HRH3 (0.39) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL28345030 | 0.85 | HRH3 (0.35) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL6358686 | 0.83 | TSHR (0.38) | HRH3RAPGEF4CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL18481438 | 0.83 | RAPGEF4 (0.41) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL893003 | 0.82 | ALDH1A1 (0.41) | HTR1DHTR1BALDH1A1CYP1A2TSHR | |
| SCHEMBL20669669 | 0.81 | KMT2A (0.37) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL16670956 | 0.80 | TRPA1 (0.33) | HTR1DHTR1BALDH1A1TSHR | |
| SCHEMBL21749452 | 0.80 | HTR1D (0.41) | HTR1DHTR1BALDH1A1KDM4EMEN1 | |
| SCHEMBL4781281 | 0.79 | HRH3 (0.36) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL954081 | 0.78 | RAPGEF4 (0.35) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221956-A | Negative thermal quenching fluorescent material with wide temperature range and preparation method and application thereof | 常州大学 | 2024-06-21 | — | — | CN | claimed |
| CN-117654298-A | Polyamine acid-base resistant composite filter membrane, preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2024-03-08 | — | — | CN | claimed |
| CN-115746270-B | High-specific-surface-area super-crosslinked polymer with controllable porosity and preparation method and application thereof | 中南民族大学 | 2024-01-30 | — | — | CN | claimed |
| CN-115403767-B | Preparation method of cationic organic polymer and adsorption application of cationic organic polymer to perrhenate | 南昌大学 | 2023-10-03 | — | — | CN | claimed |
| CN-115746270-A | Porosity-controllable high-specific-surface-area super-crosslinked polymer and preparation method and application thereof | 中南民族大学 | 2023-03-07 | — | — | CN | claimed |
| CN-115403767-A | Preparation method of cationic organic polymer and application of cationic organic polymer to adsorption of perrhenate | 南昌大学 | 2022-11-29 | — | — | CN | claimed |
| CN-111939985-B | Core-shell composite catalytic material and preparation method thereof | 青岛科技大学 | 2022-06-24 | — | — | CN | claimed |
| CN-114213422-A | Superphanes super-sweet compound and preparation method and application thereof | 湖南大学 | 2022-03-22 | — | — | CN | claimed |
| CN-114014466-A | Method for extracting calcium-iron slag filler from nickel sulfate refining wastewater | 宁波正博能源科技股份有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-112812317-A | Dawson type polyacid-based metal-TBTZ ligand organic framework material and preparation method and application thereof | 太原科技大学 | 2021-05-18 | — | — | CN | claimed |
| CN-111978337-A | Rare earth supermolecule inclusion compound and preparation method and application thereof | 湖北大学 | 2020-11-24 | — | — | CN | claimed |
| CN-111939985-A | Core-shell type composite catalytic material and preparation method thereof | 青岛科技大学 | 2020-11-17 | — | — | CN | claimed |
| CN-105940304-A | Detection of cleavage activity of an enzyme | 莫罗吉有限公司 | 2016-09-14 | — | — | CN | claimed |
| CN-104250231-B | For the synthesis of the benzotriazole ionic liquid of toluencediamine base alkyl formate | SHAANXI COAL AND CHEMICAL TECHNOLOGY DEVELOPMENT CENTER CO., LTD. (CN) | 2016-04-06 | — | — | CN | claimed |
| EP-0454270-B1 | Catalyst compositions | SHELL INT RESEARCH (NL) | 1993-12-15 | — | — | EP | claimed |
| EP-0454270-A1 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-10-30 | — | — | EP | claimed |
| US-20250205232-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-26 | — | — | US | disclosed |
| WO-2025124459-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR, AND PREPARATION AND USE THEREFOR | 石家庄以岭药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| US-4335052-A | OXIDATION OF CORRESPONDING BENZYL HALIDE WITH TERITARY AMINE OXIDEIN PRESENCE OF WATER | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0031416-A1 | Process for the preparation of substituted benzaldehydes | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1981-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250205232-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | HRH3 2523/4885RAPGEF4 557/4885CYP11B1 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.