SCHEMBL7945820

SCHEMBL7945820

Cc1cc(C)c(CBr)c(C)c1C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
SLC11A2 P49281 1/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3255153 0.89 PGK1 (0.44) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL11217789 0.83 CYP3A4 (0.35) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL7702374 0.80 ALDH1A1 (0.33)
SCHEMBL13306021 0.78 PGK1 (0.38) PGK1PGK2SLC11A2
SCHEMBL29126141 0.78 CA1 (0.39) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL28337198 0.78 CYP3A4 (0.39) PGK1PGK2SLC11A2CYP3A4TSHR
SCHEMBL9628918 0.76 PGK1 (0.38) PGK1PGK2SLC11A2
SCHEMBL11169920 0.75 MEN1 (0.43) CYP3A4TSHR
SCHEMBL25949747 0.75 EZH2 (0.31)
SCHEMBL5351167 0.74 PGK1 (0.41) PGK1PGK2SLC11A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001081281-A2 METHOD FOR PRODUCING 2,3,4,6-TETRAMETHYLBENZYL HALIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-01 WO disclosed