Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258744 | 0.89 | P2RX7 (0.38) | ALDH1A1MEN1KMT2AFABP7FABP5 | |
| SCHEMBL3253969 | 0.89 | CYP2C19 (0.41) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL3258633 | 0.88 | PDPK1 (0.41) | KMT2AATMKDM4E | |
| SCHEMBL3255825 | 0.88 | PDPK1 (0.36) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3253833 | 0.84 | CES1 (0.41) | RAB9AKDM4E | |
| SCHEMBL3254386 | 0.83 | CES1 (0.43) | RAB9AKDM4E | |
| SCHEMBL3258350 | 0.83 | SLC6A2 (0.39) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL3258561 | 0.83 | PDPK1 (0.39) | MEN1KMT2AATMTDP1 | |
| SCHEMBL3257098 | 0.82 | TAAR1 (0.39) | KMT2A | |
| SCHEMBL3248922 | 0.82 | P2RX7 (0.38) | ALDH1A1GAAMEN1KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651613-B1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | AVENTIS PHARMA INC (US) | 2010-05-26 | — | — | EP | disclosed |