Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.33 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3248358 | 0.90 | ALDH1A1 (0.38) | P2RX7ALDH1A1LMNA | |
| SCHEMBL3255825 | 0.90 | PDPK1 (0.36) | TP53KDM1ARCOR1ALDH1A1KMT2A | |
| SCHEMBL3258633 | 0.90 | PDPK1 (0.41) | KDM1AKDM4EKMT2APLAAT3PLAAT5 | |
| SCHEMBL3254057 | 0.89 | TP53 (0.42) | P2RX7TP53FABP7FABP5KDM1A | |
| SCHEMBL3255405 | 0.89 | ALDH1A1 (0.41) | FABP7FABP5KDM4EALDH1A1KMT2A | |
| SCHEMBL3259233 | 0.88 | P2RX7 (0.41) | P2RX7ALDH1A1LMNA | |
| SCHEMBL3253833 | 0.86 | CES1 (0.41) | P2RX7SLC6A3KDM4ELMNAEPHX2 | |
| SCHEMBL3254386 | 0.85 | CES1 (0.43) | P2RX7SLC6A3KDM4ELMNAEPHX2 | |
| SCHEMBL3258561 | 0.84 | PDPK1 (0.39) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL3248922 | 0.84 | P2RX7 (0.38) | P2RX7ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651613-B1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | AVENTIS PHARMA INC (US) | 2010-05-26 | — | — | EP | disclosed |