Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 16/20 | 0.68 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.68 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.68 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.68 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.68 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137816 | 0.82 | PARP10 (1.00) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL17394554 | 0.76 | TSHR (0.33) | ALDH1A1KMT2A | |
| SCHEMBL3256252 | 0.75 | ALDH1A1 (0.61) | PARP10ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL6631245 | 0.75 | PARP10 (1.00) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| Terephthalamide SCHEMBL4205368 | 0.75 | PARP10 (1.00) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL606429 | 0.75 | PARP10 (1.00) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL26416903 | 0.75 | PARP10 (1.00) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL24592196 | 0.73 | PARP10 (0.79) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL3013339 | 0.73 | PARP10 (0.79) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL6630663 | 0.73 | PARP10 (0.79) | PARP10PARP15PARP14PARP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065310-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | VIA PHARMACEUTICALS, INC (US) | 2010-06-10 | — | — | WO | disclosed |