Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGAV | P06756 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925480 | 0.83 | ITGB3 (0.50) | ITGB3ITGAVALDH1A1KDM4ETDP1 | |
| SCHEMBL2925340 | 0.75 | ITGB3 (0.42) | ITGB3ITGAVALDH1A1ITGA2BMGLL | |
| SCHEMBL547914 | 0.66 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL2906666 | 0.66 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL2917750 | 0.65 | ITGB3 (0.91) | ITGB3ITGAVITGA2B | |
| SCHEMBL5857867 | 0.62 | GABBR2 (0.50) | ITGB3ITGAV | |
| SCHEMBL4919120 | 0.61 | SIGMAR1 (0.49) | ALDH1A1KDM4ETDP1HSD11B1USP2 | |
| SCHEMBL10154308 | 0.60 | ITGB3 (0.41) | ITGB3ITGAV | |
| SCHEMBL2503391 | 0.60 | OPRK1 (0.44) | ITGB3ITGAVKDM4E | |
| SCHEMBL1244906 | 0.60 | SMN1; SMN2 (0.69) | ALDH1A1KDM4ETDP1HSD11B1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |