⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064406 | 0.83 | L3MBTL1 (0.30) | — | |
| SCHEMBL6922350 | 0.82 | TP53 (0.34) | — | |
| SCHEMBL6922352 | 0.82 | TP53 (0.34) | — | |
| Ethylene Glycol SCHEMBL9177347 | 0.78 | L3MBTL1 (0.31) | — | |
| SCHEMBL8991928 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL11121812 | 0.69 | FAAH (0.34) | — | |
| SCHEMBL11878881 | 0.67 | — | — | |
| SCHEMBL8657039 | 0.66 | CYP3A4 (0.30) | — | |
| SCHEMBL26303973 | 0.66 | CAPN1 (0.41) | — | |
| SCHEMBL26304759 | 0.64 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066714-B1 | ABRASION AND/OR SCRATCH RESISTANT ARTICLE COMPRISING AN IMPACT RESISTANT PHOTOCHROMIC POLYURETHANE COATING, AND PROCESS OF PREPARATION THEREOF | ESSILOR INT (FR) | 2018-04-11 | — | — | EP | disclosed |
| US-20100119802-A1 | Abrasion and/or Scratch Resistant Article Comprising an Impact Resistant Photochromic Polyurethane Coating, and Process of Preparation Thereof | FORD CHRISTY | 2010-05-13 | — | — | US | disclosed |
| US-7662433-B2 | impact resistant, abrasion and/or scratch resistant photochromic article comprising a substrate having two main faces, comprising: preparing a curable coating composition comprising at least one unblocked polyisocyanate terminated polyurethane pre-polymer, at least one polyol and a photochromic article | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-02-16 | — | — | US | disclosed |
| EP-2066714-A1 | ABRASION AND/OR SCRATCH RESISTANT ARTICLE COMPRISING AN IMPACT RESISTANT PHOTOCHROMIC POLYURETHANE COATING, AND PROCESS OF PREPARATION THEREOF | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008031879-A1 | ABRASION AND/OR SCRATCH RESISTANT ARTICLE COMPRISING AN IMPACT RESISTANT PHOTOCHROMIC POLYURETHANE COATING, AND PROCESS OF PREPARATION THEREOF | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2008-03-20 | — | — | WO | disclosed |
| US-20080067701-A1 | Abrasion and/or Scratch Resistant Article Comprising an Impact Resistant Photochromic Polyurethane Coating, and Process of Preparation Thereof | ESSILOR INTERNATIONAL (FR) | 2008-03-20 | — | — | US | disclosed |