Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2869529 | 0.79 | MAPT (0.50) | NAMPTMAPTHPGDTSHRTAAR1 | |
| SCHEMBL3257364 | 0.69 | NR3C1 (0.51) | MAPTHPGDTSHRHSD17B10GAA | |
| SCHEMBL10769451 | 0.68 | PTGES (0.58) | MAPTTSHRHSD17B10GAAL3MBTL1 | |
| SCHEMBL7491784 | 0.67 | LMNA (0.70) | MAPTHPGDGAAL3MBTL1FAAH | |
| SCHEMBL2097874 | 0.67 | GAA (0.65) | NAMPTGAAL3MBTL1FAAH | |
| SCHEMBL2097878 | 0.67 | GAA (0.69) | TSHRGAAL3MBTL1FAAH | |
| SCHEMBL10074139 | 0.67 | GAA (0.61) | GAAL3MBTL1FAAH | |
| SCHEMBL5218334 | 0.65 | FAAH (0.70) | TSHRGAAL3MBTL1FAAH | |
| SCHEMBL9885419 | 0.65 | FAAH (0.68) | MAPTHPGDGAAL3MBTL1FAAH | |
| SCHEMBL2091833 | 0.65 | FAAH (0.70) | GAAL3MBTL1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747196-B1 | SUBSTITUTED ARYL ACYLTHIOUREAS AND RELATED COMPOUNDS; INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS INC (US) | 2010-02-10 | — | — | EP | claimed |