Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259557 | 0.89 | MAPT (0.35) | NPC1RAB9AMAPTGAAPKM | |
| SCHEMBL3259559 | 0.86 | MAPT (0.34) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3259110 | 0.80 | GAA (0.39) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3257006 | 0.78 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3263363 | 0.75 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3258965 | 0.75 | SMN1; SMN2 (0.35) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL13765433 | 0.75 | — | — | |
| SCHEMBL3258983 | 0.74 | MAPT (0.35) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL3261243 | 0.68 | MAPT (0.33) | NPC1RAB9AMAPTGAAPKM | |
| SCHEMBL8630244 | 0.66 | MAPT (0.37) | NPC1RAB9ASMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709636-B2 | Pyrazole sulfonylurea compound and herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-05-04 | — | — | US | disclosed |
| US-7709636-B2 | Pyrazole sulfonylurea compound and herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-05-04 | — | — | US | disclosed |
| US-20100016584-A1 | Pyrazole sulfonylurea compound and herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20100016584-A1 | Pyrazole sulfonylurea compound and herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| US-7557067-B2 | Pyrazole sulfonylurea compound and herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-7557067-B2 | Pyrazole sulfonylurea compound and herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20080064600-A1 | Pyrazole Sulfonylurea Compound and Herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080064600-A1 | Pyrazole Sulfonylurea Compound and Herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| EP-1748047-A1 | PYRAZOLE SULFONYLUREA COMPOUND AND HERBICIDE | Nissan Chemical Industries, Ltd. (JP) | 2007-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016584-A1 | Pyrazole sulfonylurea compound and herbicide | PDXK, HCN3, SLC6A9 | NPC1 4567/4885RAB9A 220/4885SMN1; SMN2 4004/4885 |
| US-20080064600-A1 | Pyrazole Sulfonylurea Compound and Herbicide | GLP1R, MSRB3, PDXK | NPC1 4627/4885RAB9A 1287/4885SMN1; SMN2 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.