Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258579 | 1.00 | CHRNB2 (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4BCL2 | |
| SCHEMBL3196968 | 0.94 | PPARA (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4BCL2 | |
| SCHEMBL1803270 | 0.94 | PPARA (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4BCL2 | |
| SCHEMBL13269910 | 0.94 | PPARA (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4BCL2 | |
| SCHEMBL13269909 | 0.94 | PPARA (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4BCL2 | |
| SCHEMBL373404 | 0.90 | PPARG (0.38) | POLBAPEX1HTTTDP1PRKCG | |
| SCHEMBL14365358 | 0.88 | PPARA (0.33) | POLBHTTTDP1NPSR1PPARG | |
| SCHEMBL373648 | 0.86 | L3MBTL1 (0.39) | HTTNPSR1PPARGPPARAALDH1A1 | |
| SCHEMBL16693261 | 0.86 | L3MBTL1 (0.39) | HTTNPSR1PPARGPPARAALDH1A1 | |
| SCHEMBL3184503 | 0.86 | ESRRG (0.33) | POLBHTTNPSR1PPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867683-B1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO LTD (JP) | 2012-10-17 | — | — | EP | claimed |
| EP-1867683-B1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO LTD (JP) | 2012-10-17 | — | — | EP | disclosed |
| CN-101151332-B | Novel polymerizable dye and ophthalmic lens containing the same | MENICON CO LTD | 2010-12-08 | — | — | CN | disclosed |
| US-7662937-B2 | Polymerizable dye and ophthalmic lens containing the same | MENICON CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090082553-A1 | Novel Polymerizable Dye and Ophthalmic Lens Containing the Same | MENICON CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| CN-101151332-A | Novel polymerizable dye and ophthalmic lens containing the same | MENICON CO LTD (JP) | 2008-03-26 | — | — | CN | disclosed |
| EP-1867683-A1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO., LTD. (JP) | 2007-12-19 | — | — | EP | disclosed |