Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 8/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868695 | 0.83 | RAB9A (0.42) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL3257336 | 0.75 | LMNA (0.44) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL205645 | 0.74 | CFTR (0.59) | ALDH1A1LMNAMAPTMEN1POLB | |
| SCHEMBL4361562 | 0.71 | MAPT (0.55) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL2863704 | 0.71 | MAPT (0.54) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL2873151 | 0.71 | MAPT (0.54) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL3252126 | 0.71 | OXTR (0.43) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL2865576 | 0.70 | S1PR4 (0.44) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL2871229 | 0.69 | SMPD1 (0.53) | ALDH1A1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL3258918 | 0.69 | S1PR1 (0.50) | RAB9ASMN1; SMN2CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747196-B1 | SUBSTITUTED ARYL ACYLTHIOUREAS AND RELATED COMPOUNDS; INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS INC (US) | 2010-02-10 | — | — | EP | claimed |