Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513 | 0.87 | — | — | |
| SCHEMBL16694372 | 0.85 | — | — | |
| SCHEMBL6169040 | 0.85 | — | — | |
| Iodide SCHEMBL13274496 | 0.85 | — | — | |
| Ethane SCHEMBL15300165 | 0.85 | — | — | |
| SCHEMBL4304356 | 0.78 | — | — | |
| SCHEMBL18917184 | 0.70 | ALDH1A1 (0.64) | — | |
| SCHEMBL8563693 | 0.69 | NPC1 (0.30) | — | |
| SCHEMBL2011890 | 0.67 | — | — | |
| 1-Methylimidazole SCHEMBL11120817 | 0.67 | QPCT (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059546-B2 | SAGGING CONTROL AGENTS | COATINGS FOREIGN IP CO LLC (US) | 2018-09-19 | — | — | EP | disclosed |
| EP-2059548-B1 | AQUEOUS COMPOSITIONS OF SAGGING CONTROL AGENTS | COATINGS FOREIGN IP CO LLC (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2059546-B1 | SAGGING CONTROL AGENTS | COATINGS FOREIGN IP CO LLC (US) | 2015-03-11 | — | — | EP | disclosed |
| US-7662875-B2 | Aqueous coating compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| CN-101511897-A | Aqueous compositions of sagging control agents | DU PONT (US) | 2009-08-19 | — | — | CN | disclosed |
| EP-2059546-A1 | SAGGING CONTROL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-20 | — | — | EP | disclosed |
| EP-2059548-A2 | AQUEOUS COMPOSITIONS OF SAGGING CONTROL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-20 | — | — | EP | disclosed |
| US-20080132638-A1 | Aqueous compositions of sagging control agents | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-06-05 | — | — | US | disclosed |
| US-20080132639-A1 | Sagging control agents | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-06-05 | — | — | US | disclosed |
| WO-2008030445-A1 | SAGGING CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008030437-A2 | AQUEOUS COMPOSITIONS OF SAGGING CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-13 | — | — | WO | disclosed |
| US-20060270782-A1 | Aqueous coating compositions | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2006-11-30 | — | — | US | disclosed |