⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513 | 0.97 | — | — | |
| Ethane SCHEMBL15300165 | 0.94 | — | — | |
| Iodide SCHEMBL13274496 | 0.94 | — | — | |
| SCHEMBL16694372 | 0.94 | — | — | |
| Piperazine SCHEMBL3259121 | 0.85 | — | — | |
| SCHEMBL18917184 | 0.78 | ALDH1A1 (0.64) | — | |
| SCHEMBL8563693 | 0.76 | NPC1 (0.30) | — | |
| SCHEMBL2011890 | 0.75 | — | — | |
| 1-Methylimidazole SCHEMBL11120817 | 0.75 | QPCT (0.56) | — | |
| SCHEMBL30950402 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285588-C | Farnesyl protein transferase inhibitors | SCHERING CORP (US) | 2006-11-22 | — | — | CN | disclosed |
| EP-1140904-B1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORP (US) | 2005-04-20 | — | — | EP | disclosed |
| US-6800636-B2 | FOR THERAPY OF CANCER | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-20030040520-A1 | Farnesyl protein transferase inhibitors | GUZI TIMOTHY (US) | 2003-02-27 | — | — | US | disclosed |
| CN-1352642-A | Farnesyl protein transferase inhibitors | SCHERING CORP (US) | 2002-06-05 | — | — | CN | disclosed |
| US-6362188-B1 | ANTICANCER AGENTS | SCHERING CORPORATION | 2002-03-26 | — | — | US | disclosed |
| EP-1140904-A1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037458-A1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2000-06-29 | — | — | WO | disclosed |