Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.35 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18198917 | 0.76 | — | — | |
| SCHEMBL9400047 | 0.67 | GPR84 (0.38) | ACHEBACE1GPR84ALDH1A1ALOX5 | |
| SCHEMBL28655350 | 0.67 | ACHE (0.55) | ACHEBACE1GPR84ALDH1A1ALOX5 | |
| SCHEMBL9889220 | 0.64 | ACHE (0.47) | ACHEBACE1GPR84ALDH1A1ALOX5 | |
| Hydrochloric Acid SCHEMBL28922225 | 0.64 | ACHE (0.57) | ACHEBACE1GPR84ALDH1A1ALOX5 | |
| SCHEMBL1101628 | 0.63 | ACHE (0.67) | ACHEBACE1PTPN1GPR84ALDH1A1 | |
| SCHEMBL6754258 | 0.63 | ACHE (0.50) | ACHEBACE1GPR84ALDH1A1ALOX5 | |
| Benzoquinone SCHEMBL11072887 | 0.62 | ACHE (0.54) | ACHEBACE1GPR84ALDH1A1ALOX5 | |
| SCHEMBL9588146 | 0.61 | ACHE (0.70) | ACHEBACE1PTPN1GPR84ALDH1A1 | |
| SCHEMBL13174567 | 0.61 | ACHE (0.70) | ACHEBACE1PTPN1GPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718277-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718087-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7704610-B2 | organic light emitting device comprising deuterated organic iridium complex; optoelectronic devices, photovoltaic devices; enhanced color properties and light output efficiencies | GENERAL ELECTRIC COMPANY (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100090586-A1 | ELECTRONIC DEVICES COMPRISING ORGANIC IRIDIUM COMPOSITIONS | GENERAL ELECTRIC COMPANY | 2010-04-15 | — | — | US | disclosed |
| US-7695640-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-04-13 | — | — | US | disclosed |
| US-7691494-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-7691292-B2 | organic light emitters; photovoltaic cells; electrophosphorescent | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-20100051869-A1 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY | 2010-03-04 | — | — | US | disclosed |
| US-7652151-B2 | Ketopyrroles useful as ligands in organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-01-26 | — | — | US | disclosed |
| US-7608677-B2 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| EP-2049555-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2009-04-22 | — | — | EP | disclosed |
| US-20080023672-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026249-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026250-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080023671-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| WO-2008014037-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |
| US-20080026477-A1 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | OR10J3, OPRD1, OCIAD1 | ACHE 3907/4885BACE1 4246/4885PTPN1 3215/4885 |
| US-20100051869-A1 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | OCIAD1, OCIAD2, OXER1 | ACHE 3685/4885BACE1 4118/4885PTPN1 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.