Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 19/20 | 0.44 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.44 |
| ▸ | XIAP | P98170 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655350 | 0.89 | ACHE (0.55) | ACHEBACE1ALOX5MPEG1XIAP | |
| Hydrochloric Acid SCHEMBL28922225 | 0.84 | ACHE (0.57) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL6754278 | 0.84 | ACHE (0.53) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL7866839 | 0.81 | ACHE (0.47) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL21814448 | 0.79 | ACHE (0.47) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL9889220 | 0.79 | ACHE (0.47) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL8933270 | 0.78 | ACHE (0.50) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL5554116 | 0.78 | ALOX5 (0.62) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL21814670 | 0.78 | ACHE (0.50) | ACHEBACE1ALOX5MPEG1XIAP | |
| SCHEMBL21814489 | 0.78 | ACHE (0.50) | ACHEBACE1ALOX5MPEG1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828347-B2 | Reacting a hydroxyquinone anion with a first quinone possessing a first directing group at a C-2 of the first quinone and a second directing group at a C-3 of the first quinone and obtaining a biquinone | ILLINOIS INSTITUTE OF TECHNOLOGY | 2004-12-07 | — | — | US | disclosed |
| US-20040087663-A1 | Anti-viral multi-quinone compounds and regiospecific synthesis thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087663-A1 | Anti-viral multi-quinone compounds and regiospecific synthesis thereof | NQO1, QTRT1, NQO2 | ACHE 4537/4885BACE1 2911/4885ALOX5 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.