Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 10/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87287 | 0.80 | MAOB (0.40) | HTTMAOBCYP19A1CYP3A4CYP2C19 | |
| SCHEMBL9286065 | 0.73 | LMNA (0.65) | NPSR1LMNAHTTL3MBTL1TSHR | |
| SCHEMBL4618757 | 0.73 | TSHR (0.47) | NPSR1L3MBTL1PKMTSHRMAOB | |
| SCHEMBL11386178 | 0.73 | PKM (0.38) | NPSR1LMNAHTTL3MBTL1PKM | |
| SCHEMBL2156976 | 0.73 | APEX1 (0.44) | NPSR1LMNAHTTL3MBTL1PKM | |
| SCHEMBL11382497 | 0.72 | PKM (0.40) | NPSR1PKMTSHRMAOBCYP19A1 | |
| SCHEMBL2156979 | 0.71 | PRKCA (0.44) | LMNAPKMTSHRALDH1A1CYP3A4 | |
| SCHEMBL9136839 | 0.69 | PKM (0.47) | NPSR1PKMTSHRMAOBCYP19A1 | |
| SCHEMBL29448029 | 0.69 | PKM (0.47) | NPSR1LMNAL3MBTL1PKMTSHR | |
| SCHEMBL4618755 | 0.69 | TSHR (0.47) | NPSR1L3MBTL1PKMTSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671220-B2 | Processes for the 3,3-dialkylation of 4-chromanones | WYETH (US) | 2010-03-02 | — | — | US | disclosed |
| WO-2006089008-A2 | PROCESSES FOR THE 3,3-DIALKYLATION OF 4-CHROMANONES | WYETH (US) | 2006-08-24 | — | — | WO | disclosed |
| US-20060183924-A1 | Processes for the 3,3-dialkylation of 4-chromanones | WYETH (US) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183924-A1 | Processes for the 3,3-dialkylation of 4-chromanones | GCK, KHK, CDYL | NPSR1 4252/4885LMNA 2407/4885HTT 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.