Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262911 | 0.78 | NPC1 (0.41) | NPC1RAB9AKDM4ECNR1GPR55 | |
| SCHEMBL16202074 | 0.74 | CNR1 (0.47) | NPC1RAB9AKDM4ECNR1GPR55 | |
| SCHEMBL7095866 | 0.73 | KDM4E (0.50) | NPC1RAB9AKDM4ECNR1GPR55 | |
| SCHEMBL7859575 | 0.70 | CNR1 (0.54) | KDM4ECNR1GPR55CNR2GPR35 | |
| SCHEMBL3264376 | 0.70 | CYP1A2 (0.40) | NPC1RAB9ACNR1ATMPOLB | |
| SCHEMBL3264878 | 0.70 | CYP1A2 (0.40) | NPC1RAB9AATMPOLBKMT2A | |
| SCHEMBL13806032 | 0.68 | ALDH1A1 (0.43) | NPC1RAB9ACNR1GPR55GPR35 | |
| SCHEMBL16202073 | 0.67 | CNR1 (0.47) | NPC1RAB9AKDM4ECNR1GPR55 | |
| SCHEMBL5904573 | 0.67 | KDM4E (0.42) | NPC1RAB9AKDM4ECNR1GPR55 | |
| SCHEMBL3263702 | 0.67 | ATM (0.43) | NPC1RAB9ACNR1CNR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |