Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.36 |
| ▸ | KHK | P50053 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265119 | 0.85 | NPSR1 (0.47) | ALDH1A1L3MBTL1RIPK1SIGMAR1NPSR1 | |
| SCHEMBL3386827 | 0.84 | POLB (0.46) | ALDH1A1L3MBTL1RIPK1MAPTHPGD | |
| SCHEMBL3260375 | 0.82 | GRM1 (0.40) | ALDH1A1L3MBTL1 | |
| SCHEMBL19068631 | 0.76 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1RIPK1MAPTHPGD | |
| SCHEMBL3262626 | 0.76 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1MAPTHPGDNPSR1 | |
| SCHEMBL3263786 | 0.74 | POLB (0.46) | ALDH1A1L3MBTL1MAPTHPGDNPSR1 | |
| SCHEMBL15825247 | 0.74 | RIPK1 (0.40) | ALDH1A1L3MBTL1RIPK1MAPTHPGD | |
| SCHEMBL3261172 | 0.74 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL3325578 | 0.73 | MAPT (0.54) | ALDH1A1L3MBTL1MAPTHPGDNPSR1 | |
| SCHEMBL3261554 | 0.70 | BAZ2B (0.35) | ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |