Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3261170 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL3259811 | 0.79 | MEN1 (0.34) | GPR3MEN1POLBKMT2AATM | |
| SCHEMBL3260464 | 0.78 | GPR3 (0.36) | GPR3MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL3260395 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3260904 | 0.74 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL3201535 | 0.74 | ADRA2A (0.35) | GPR3MEN1POLBKMT2AATM | |
| SCHEMBL28856362 | 0.73 | GABRA1 (0.41) | GPR3MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL3259639 | 0.71 | — | — | |
| SCHEMBL3213756 | 0.70 | MEN1 (0.40) | GPR3MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL3259523 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671226-B2 | Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| US-7439379-B2 | Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-10-21 | — | — | US | disclosed |