Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 5/20 | 0.35 |
| ▸ | THRB | P10828 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137803 | 0.89 | KDM4E (0.51) | KDM4EGAAMAPK1SMN1; SMN2LMNA | |
| SCHEMBL3256884 | 0.87 | KDM4E (0.37) | KDM4EGAAMAPK1SMN1; SMN2LMNA | |
| SCHEMBL4449560 | 0.85 | GAA (0.35) | KDM4EGAAMAPK1SMN1; SMN2LMNA | |
| SCHEMBL14392218 | 0.82 | KDM4E (0.47) | KDM4EGAAMAPK1SMN1; SMN2LMNA | |
| SCHEMBL4440700 | 0.75 | KDM4E (0.51) | KDM4EGAAMAPK1SMN1; SMN2HPGD | |
| SCHEMBL3130752 | 0.74 | GAA (0.53) | KDM4EGAAMAPK1LMNAMAPT | |
| SCHEMBL4527269 | 0.73 | THRA (0.48) | KDM4ESMN1; SMN2THRATHRBALDH1A1 | |
| SCHEMBL4298109 | 0.72 | GAA (0.43) | KDM4EGAAMAPK1SMN1; SMN2LMNA | |
| SCHEMBL3914754 | 0.71 | USP2 (0.44) | KDM4EGAAMAPK1SMN1; SMN2LMNA | |
| SCHEMBL3925471 | 0.70 | THRA (0.46) | KDM4ESMN1; SMN2THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | TSHR, GHSR, TRHR | KDM4E 1562/4885GAA 1547/4885MAPK1 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.