Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298109 | 0.90 | GAA (0.43) | GAAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3256884 | 0.85 | KDM4E (0.37) | GAASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL3260468 | 0.85 | KDM4E (0.41) | GAAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3130752 | 0.78 | GAA (0.53) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL5859445 | 0.76 | LMNA (0.42) | GAAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL27874611 | 0.75 | ALDH1A1 (0.42) | GAAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3137803 | 0.73 | KDM4E (0.51) | GAAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3910714 | 0.73 | KMT2A (0.46) | GAAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3909957 | 0.73 | KMT2A (0.46) | GAAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3909800 | 0.73 | ALDH1A1 (0.39) | GAAMAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318514-A1 | Novel Pharmaceutical Compositions | KARO BIO AB (SE) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318514-A1 | Novel Pharmaceutical Compositions | TSHR, TRHR, THRA | GAA 3977/4885MAPT 3554/4885SMN1; SMN2 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.