Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.33 |
| ▸ | F12 | P00748 | 5/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3264285 | 0.79 | LTA4H (0.33) | — | |
| SCHEMBL7835340 | 0.72 | ALDH1A1 (0.33) | F12F2 | |
| SCHEMBL28639323 | 0.68 | F12 (0.36) | F12F2 | |
| SCHEMBL900236 | 0.68 | REN (0.42) | RENCA1CA2CA4CA9 | |
| SCHEMBL20141289 | 0.68 | REN (0.42) | RENCA1CA2CA4CA9 | |
| SCHEMBL10565873 | 0.67 | F12 (0.40) | F12F2 | |
| SCHEMBL5719329 | 0.67 | CA1 (0.62) | RENCA1CA2CA4CA9 | |
| SCHEMBL4749948 | 0.67 | CA1 (0.62) | RENCA1CA2CA4CA9 | |
| SCHEMBL3495230 | 0.67 | CA1 (0.62) | RENCA1CA2CA4CA9 | |
| SCHEMBL4288512 | 0.66 | LTA4H (0.52) | RENCA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170831-A1 | BENZAZEPINE DERIVATIVES USEFUL AS VASOPRESSIN ANTAGONISTS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009001968-A1 | BENZAZEPINE DERIVATIVES USEFUL AS VASOPRESSIN ANTAGONISTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-12-31 | — | — | WO | disclosed |