Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173900 | 0.90 | ALDH1A1 (0.41) | HTTALDH1A1TSHRABCB1SIRT2 | |
| SCHEMBL3258435 | 0.84 | HCRTR1 (0.51) | HTTALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL3258412 | 0.82 | LMNA (0.50) | HTTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL3261086 | 0.81 | IRAK4 (0.59) | HTTALDH1A1IRAK4LMNAKDM4E | |
| SCHEMBL3260590 | 0.81 | LMNA (0.56) | HTTALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL3261986 | 0.79 | HPGD (0.49) | HTTALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3259032 | 0.79 | HTT (0.53) | HTTALDH1A1LMNAPARP1MEN1 | |
| SCHEMBL13763533 | 0.77 | HTT (0.71) | HTTALDH1A1TSHRABCB1SIRT2 | |
| SCHEMBL3339926 | 0.76 | ABCB1 (0.64) | HTTALDH1A1TSHRABCB1LMNA | |
| SCHEMBL477006 | 0.76 | ALDH1A1 (0.59) | HTTALDH1A1TSHRABCB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952189-B2 | Process for preparing diaryl carbonates or alkyl aryl carbonates from dialkyl carbonates | BAYER MATERIALSCIENCE AG (DE) | 2015-02-10 | — | — | US | disclosed |
| US-20100261928-A1 | PROCESS FOR PREPARING DIARYL CARBONATES OR ALKYL ARYL CARBONATES FROM DIALKYL CARBONATES | BAYER MATERIALSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261928-A1 | PROCESS FOR PREPARING DIARYL CARBONATES OR ALKYL ARYL CARBONATES FROM DIALKYL CARBONATES | HDHD5, AHR, AGL | HTT 1154/4885ALDH1A1 3535/4885TSHR 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.