Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263382 | 0.78 | ALDH1A1 (0.53) | KDM4EGAAALDH1A1MAPTTHRB | |
| SCHEMBL4872103 | 0.73 | GAA (0.60) | KDM4EGAAALDH1A1MAPTTHRB | |
| SCHEMBL28409089 | 0.73 | MEN1 (0.48) | KDM4EGAAALDH1A1MAPTNPC1 | |
| SCHEMBL29809206 | 0.72 | ALDH1A1 (0.67) | KDM4EGAAALDH1A1MAPTTSHR | |
| SCHEMBL3262685 | 0.69 | GSK3B (0.51) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3561082 | 0.69 | MAPT (0.48) | KDM4EGAAALDH1A1MAPTTHRB | |
| SCHEMBL11685438 | 0.66 | MCL1 (0.45) | KDM4EGAAALDH1A1MAPTTHRB | |
| SCHEMBL11689636 | 0.65 | ALDH1A1 (0.47) | KDM4EGAAALDH1A1MAPTNPC1 | |
| SCHEMBL11308251 | 0.64 | — | — | |
| Sulfuric Acid SCHEMBL11767295 | 0.64 | CYP1A2 (0.52) | ALDH1A1MEN1KMT2APTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |