Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261864 | 0.78 | KDM4E (0.46) | ALDH1A1MAPTKDM4EGSK3BGAA | |
| SCHEMBL525877 | 0.73 | MAPT (0.59) | ALDH1A1PARP1PLK4MAPK9LIMK1 | |
| SCHEMBL3262685 | 0.72 | GSK3B (0.51) | ALDH1A1MAPTKDM4EGSK3BTDP1 | |
| SCHEMBL7710988 | 0.71 | ALDH1A1 (0.67) | ALDH1A1PARP1MAPTKDM4EPDE4A | |
| SCHEMBL3485414 | 0.70 | ALDH1A1 (1.00) | ALDH1A1PARP1MAPTKDM4EGAA | |
| SCHEMBL11434922 | 0.67 | ALDH1A1 (0.53) | ALDH1A1PARP1PLK4MAPK9LIMK1 | |
| SCHEMBL4208272 | 0.67 | PARP1 (1.00) | ALDH1A1PARP1PLK4LIMK1CLK4 | |
| SCHEMBL27501679 | 0.65 | MEN1 (0.50) | ALDH1A1MAPTKDM4ETDP1HDAC4 | |
| SCHEMBL27530459 | 0.65 | LMNA (0.50) | ALDH1A1PARP1MAPTKDM4EHDAC4 | |
| Anthraquinone SCHEMBL27283959 | 0.64 | MEN1 (0.75) | ALDH1A1MAPTKDM4EHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713964-B2 | Methods for treating asthmatic conditions | WYETH LLC (US) | 2010-05-11 | — | — | US | disclosed |
| US-7713964-B2 | Methods for treating asthmatic conditions | WYETH LLC (US) | 2010-05-11 | — | — | US | disclosed |
| US-20100093725-A1 | SEMI-SOLID FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | WYETH | 2010-04-15 | — | — | US | disclosed |
| US-20100056520-A1 | FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | WYETH | 2010-03-04 | — | — | US | disclosed |
| US-20100056520-A1 | FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | WYETH | 2010-03-04 | — | — | US | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008055146-A9 | FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | WYETH CORP (US) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008055136-A2 | LIQUID FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | WYETH (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008055146-A2 | FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | WYETH (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008055148-A2 | SEMI-SOLID FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | WYETH (US) | 2008-05-08 | — | — | WO | disclosed |
| EP-0313021-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-26 | — | — | EP | disclosed |
| US-RE30420-E | DIURETIC, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-21 | — | — | US | disclosed |
| US-4112227-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
| US-4056533-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS, DIURETICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |
| US-4000294-A | DIURESIS OR SALURESIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3992404-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVE AGENTS, AND ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | disclosed |
| US-3952008-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056520-A1 | FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | PLA2G4B, PLA2G4A, PLA2G1B | ALDH1A1 2802/4885PARP1 1596/4885PLK4 2501/4885 |
| US-20100093725-A1 | SEMI-SOLID FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS | PLA2G4A, PLA2G2D, PLA2G4B | ALDH1A1 3246/4885PARP1 1850/4885PLK4 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.