Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711906 | 0.85 | — | — | |
| SCHEMBL3258818 | 0.72 | ALDH1A1 (0.46) | — | |
| SCHEMBL4718364 | 0.61 | GRIA1 (0.38) | — | |
| SCHEMBL28847260 | 0.59 | GRIA1 (0.42) | — | |
| SCHEMBL4720108 | 0.59 | PTGDR2 (0.37) | — | |
| SCHEMBL4718308 | 0.59 | P2RX7 (0.36) | — | |
| SCHEMBL11132912 | 0.59 | MEN1 (0.39) | — | |
| SCHEMBL4762925 | 0.58 | HTR6 (0.42) | — | |
| SCHEMBL12606731 | 0.57 | LMNA (0.39) | — | |
| SCHEMBL2192295 | 0.56 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166842-A1 | TRICYCLIC ANILIDE HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008153852-A1 | TRICYCLIC ANILIDE HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2008-12-18 | — | — | WO | disclosed |