Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968476 | 0.84 | PPARG (0.52) | ALDH1A1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28741054 | 0.74 | HTT (0.46) | NOTUMALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19716861 | 0.74 | LMNA (0.46) | ALDH1A1POLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4496453 | 0.72 | PLA2G7 (0.43) | ALDH1A1POLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5660114 | 0.72 | ALDH1A1 (0.44) | ALDH1A1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21881179 | 0.71 | PPARA (0.68) | ALDH1A1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL306372 | 0.70 | F7 (0.53) | ALDH1A1GAAPOLBSLC6A2SLC6A4 | |
| SCHEMBL28341455 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GAAHTTSMN1; SMN2PPARG | |
| SCHEMBL362393 | 0.69 | F7 (0.52) | ALDH1A1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29937752 | 0.68 | ALDH1A1 (0.55) | ALDH1A1SLC6A2SLC6A4SLC6A3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015387-A1 | DAA-PYRIDINE AS PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND FOR DIAGNOSTIC IMAGING AND PHARMACEUTICAL TREATMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015340-A1 | DAA-PYRIDINE AS PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND FOR DIAGNOSTIC IMAGING AND PHARMACEUTICAL TREATMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-11 | — | — | WO | disclosed |